Volcanic disease presents new ways to produce medicinal plants, vaccines

Epilepsy is supposed to change the way new ways of giving medicine, vaccines, are available

SMV1 disease in the form of lemongrass is a serious threat to single infected organisms. Available: The Egelman Lab, UVA

From the hot volcanic springs where the water is boiled, a researcher at the University of Virginia and his colleagues discovered the presence of lemon -type diseases. And that knowledge can lead to new and better ways to produce medicines and seeds.

Although most infections are rodent or spherical (such as the coronavirus responsible for COVID-19), scientists are puzzled by the different types of infections found in some of the most dangerous areas. on Earth.

Researchers were studying some of the viruses when they discovered that there were other factors that could change its nature. Although it is similar to a lemon or spindle, the disease can develop on the tails. The way he could do that, scientists knew, might explain the healing of diseases similar to the ancient spindle spindle disease commonly seen today.

“We are now able to identify a new theory about how proteins in the brain bind to DNA in a cancer patient,” said lead researcher Edward H. Egelman of the UVA School of Medicine. “These are ideas not only to understand the development of certain diseases, but can be used for new ways to save everything from drugs to cannabis.”

The nature of the diseases

Egelman and his colleagues are studying Sulfolobus monocaudavirus 1, or SMV1, a protein that surrounds DNA in the form of a spindle or lemon. But it has been a mystery for nearly 20 years how multiple copies of the same protein can come together to form a single species.

Egelman and his team were able to demonstrate other properties of SMV1 using advanced cryo-electron microscopy and high-resolution image imaging.

SMV1, the researchers said, has chains of proteins that are smoother and smoother than each other, due to their “fatness.” These seven protein components are found in the body and tail of the patient, and they give the patient the ability to change shape. Instead of gaining a stable form, it can fly up like a pufferfish to incorporate genetics. At the same time, these fibers form an immune barrier that prevents the acid surrounding the fibers from destroying the DNA in the patient.

The disease poses a terrible threat to the same organisms it infects. Once the disease is diagnosed, the visitors will become large factories that promote the disease patients. These hospital systems are growing up to 20 times before the emergence of a new hospital network.

From what they saw, Egelman and his colleagues thought that today they were shaped like spindles or lemons that grew from ancient times. Stem pathogens can have a limited amount of DNA, and the “fat” properties allow SMV1 shapeshift to allow progenitor cells to accumulate more genetic material – a useful trait for cancer patients. , from an evolutionary perspective.

“Diseases can pose a significant threat to human health, as we know from COVID-19 disease,” said Egelman, of UVA’s Department of Biochemistry and Molecular Genetics. “So it’s important for us to understand more about how viruses grow. But we can learn from viruses, and make new technologies based on the principles that these buildings have. very simple. “

The researchers published their findings in a scientific journal Phone.


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More information:
According to Fengbin Wang et al, Spindle -specific archaeal diseases were converted from rod ancestors to attach to a larger genome, Phone (2022). DOI: 10.1016 / j.cell.2022.02.019

Journal information:
Phone

Presented by the University of Virginia

Directions: Volcanic disease shows change new ways to deliver medicines, medicines (2022, March 31) Retrieved 31 March 2022 from https://phys.org/news/2022- 03-shape-shifting-volcano-virus-ways- drugs.html

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