Babies were conceived when their mothers were actually exposed to the smoke of the fire which showed changes in nature compared to animals that were conceived in later days, according to a recent research from researchers at the California National Primate Research Center at the University of California, Davis. The work will be published on April 1st Nature Communications.
Evidence suggests the importance of time to the effects of exposure to smoke on pregnancy and suggests a teratogenic, or developmental, condition, said lead author Bill Lasley, physician emeritus of the University. public health and rehabilitation at the UC Davis School of Veterinary Medicine and Center for Health and Environment. .
“I think this is a result of future research of evidence during pregnancy, because we’ll know when to look,” Lasley said. Studies on environmental awareness during pregnancy are limited, and women may not be aware of their pregnancy until weeks into the first trimester, he said. his.
The Camp Fire, which began in Nov. 8, 2018, provides a natural experiment in smoke detection. It covered the Davis area, about 100 miles away, with smoke at the peak of the production season for rhesus macaques that lived in outdoor enclosures at the California National Primate Research Center.
The 89 animals were born about six months later. They were divided among 52 animals that were conceived before or before Nov. 22, 2018 were thought to have “revealed” fire smoke in their first trimester, and 37 raised later were not identified.
John Capitanio, a psychiatrist at UC Davis and a senior scientist at the CNPRC, has been leading routine evaluations on animals born at the Center for two years. At about 3-4 months of age, adolescents are exposed to a variety of cognitive and behavioral tests. Although the number of animals carried during the Camp Fire review was small, they could be compared not only to each other (shown vs.
In the evaluation, babies exposed to smoke showed an increased symptom of inflammation, a decrease in the cortisol response to stress, memory deficits and a better heart. passive than other animals, Capitanio said.
“It’s a simple effect on the central aspects of cognitive function,” Capitanio said. The results were consistent with those found in prenatal studies on air pollution, he said. Comparisons between the groups and animals born at different ages showed no effects due to the time of pregnancy (before the time of birth).
Effect on fetal development
Evidence suggests that a portion of the smoke bill may act as a teratogen, affecting fetal development, Lasley said. That area may contain air hydrocarbons such as phthalates, which are found in the smoke of the Camp Fire.
Unlike other mammals, the placenta of primates such as humans and rhesus macaques releases hormones that support brain growth through the adrenal system, he said.
“Because the fetal adrenal glands are the source of cortisol and other steroids for neurologic development, what determines the nature, potential of the placenta-adrenal-brain axis the teacher, ”Lasley said.
Lasley is beginning a potential study with women with embryos implanted as a result of in vitro fertilization, even though the timing of pregnancy is clear if women are exposed to smoke or fumes. Other impurities.
A study previously published on the same group of animals by Bryn Wilson, a resident OB / GYN at UC Davis Health in collaboration with Lasley and Professor Kent Pinkerton, UC Davis Center for Health and Environment, found a small, but not significant number, less. the number of births in the affected group.
Additional authors on the paper include Laura Del Rosso, California National Primate Research Center and Nancy Gee, UC Davis Center for Health and Environment. The work was supported by grants from the NIH.
Natural exposure to smoke increases the risk of reproductive loss in rhesus macaques
Adverse biobehavioral effects on infants due to exposure of rhesus macaques to fiery smoke, Nature Communications (2022). DOI: 10.1038 / s41467-022-29436-9
Directions: Detection of fire smoke during early pregnancy in relation to infant labor (2022, April 1) retrieved April 1, 2022 from https://phys.org/news/2022- 04-wildfire-exposure-early-pregnancy-affects.html
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