The old malaria puzzle was solved as an ape cause

malaria

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Scientists have solved a 100 -year mystery about the evolutionary links between malaria infections in humans and chimpanzees.

They saw the parasite P. malariae —One of the six most common forms of malaria among humans — originated in African apes before developing human disease.

Although it is often associated with mild illness, if left untreated P. malariae it can trigger chronic or life -long illnesses, the researchers said.

The evolutionary puzzle originated in the 1920s when scientists discovered chimpanzees that contracted the disease known as crab disease. P. malariae under the microscope.

The two parasites are thought to be very different, but – until now – it has not been possible to confirm because the genetic nature of the chimpanzee strain has not been studied.

Now, scientists at the University of Edinburgh, in collaboration with colleagues at the University of Pennsylvania, US, have used leading technologies to study the DNA of parasites.

They knew there were three different ways. One way—P. malariae—To harm humans, and the other two harm apes.

Some of the two ape diseases have been found in chimpanzees, gorillas and bonobos between Central and West Africa. This unprecedented species only affects the human parasite.

The other paper is more closely related to the person who is bothering the person. Knowing this allowed the researchers to make detailed comparisons of the genetic differences of the two species.

This indicated that the malaria parasite population was moving into a genetic bottleneck, where its population had decreased slightly and most of its mutations had disappeared.

Perhaps an explanation for this P. malariae an ape disease at first, but a small number of parasites have evolved to start infecting humans, the company said.

The lesson was published in a journal Nature Communications.

The lead author, Dr. Lindsey Plenderleith, of the School of Biological Sciences at the University of Edinburgh, said: “Among the six diseases that cause malaria in humans, P. malariae Which is one of the few things that is understood. Our knowledge could provide important clues about the potential to infect humans, as well as help scientists determine if parasitic parasites are re -infecting humans. ”


Ape parasite genomes reveal the cause, growth of the leading cause of the disease outside of Africa


Presented by the University of Edinburgh

Directions: The old malaria puzzle solved as an ape cause (2022, April 6) downloaded on April 6, 2022 from https://phys.org/news/2022-04-century-old-malaria -parasite-puzzle-ape.html

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