For years, scientific historians have written about the idea that using microswimmers can make cuts and deliver medications to people. Now, a team led by researchers from the University of Minnesota Twin Cities has discovered how bacteria swim through hard water and environments, just like the human body. .
Their knowledge could help scientists develop new drugs for bacterial diseases and develop bacterial systems for transporting the drugs into the human body.
The study is published in so so.
The University of Minnesota has a long history of swimming in other waters. In 2004, Ed Cussler, then a professor in the Department of Chemical Engineering and Materials Science, compared the speed at which a university athlete bathes in water with alcohol, syrupy guar gum solution. It has led to an unexpected discovery (and an IgNobel gift) that people can swim just as quickly in guar gum solutions as water.
Nearly two years later, a multidisciplinary team at the University of Minnesota re -examined the problem, except that swimmers now have more microscopic bacteria than college athletes. They found that the bacteria bathed in thick solutions faster than in water.
Scientists have studied extensively since the 1960s from the “bacterial bath,” as is commonly seen in the research community. Preliminary studies have shown that bacteria swim rapidly in thick polymer solutions, i.e. liquids containing polymers, which are made up of long molecules such as chains. The researchers speculated that this is because the bacteria can swim through a network created by chain molecules and can lengthen the chains to help them grow.
However, in this new study, the U group of M studied for the first time the movement of bacteria through the responses of small solid particles, rather than chain molecules. Despite the significant differences in polymer and particle dynamics, they found that bacterial infection swam faster, hoping to find another explanation for the movement of bacterial infection in thick and hard liquids.
Researchers U of M have a possible answer. They believe that the bacteria swim, the pull that is made from going to the parts that reach their flagella – or the bacterial bubbles in that wheel to stimulate and them forward – to fit in well with their bodies, to help them move faster.
“People have enjoyed swimming in bacteria since microscopes were invented in the 17th century, but until now, knowledge has been limited to simple liquids such as water,” he explains. Shashank Kamdar, lead author on the paper and the University of Minnesota. chemical engineering graduate student. “But it’s a broad question about how bacteria move to natural conditions, such as soil and water in their habitats.”
Understanding how bacteria move through complex and complex environments – the human body – can help scientists develop treatments for diseases and how to use them. to bacteria as a vessel for delivering drugs to humans.
“There are a number of techniques that people have used to describe this phenomenon over the years, but with this research, we provide a common understanding of what to do when swimming. bacteria through complex solutions, ”said Xiang Cheng, senior author on the paper and a consultant at. the Department of Chemical Engineering and Materials Science University of Minnesota. “And it’s important to understand how bacteria move in a complex environment. For example, certain types of bacteria cause gastrointestinal upset…”
“In the end, we have to learn from the bacteria,” Cheng added. “They’re moving forward despite the opposition.”
In addition to Cheng and Kamdar, the group includes University of Minnesota College of Science and Engineering Distinguished Professor and 3M Chair in Experiential Learning Lorraine Francis and Department of Engineering and graduate researcher Seunghwan Shin; and Beijing Computational Science Research Center researchers Premkumar Leishangthem and Xinliang Xu.
Researchers know why E. coli moves faster in liquids such as syrup than in water.
Xiang Cheng, The colloidal nature of hard liquids increases bacterial motility, so so (2022). DOI: 10.1038 / s41586-022-04509-3. www.nature.com/articles/s41586-022-04509-3
Presented by the University of Minnesota
Directions: New research on bacterial bathing can help prevent the spread of disease and improve medicinal properties (2022, March 30) Retrieved 30 March 2022 from https: // phys.org/news/2022-03-bacteria-disease-medical-treatments .html
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